ELK Biotechnology CD203c rabbit pAb
CD203c 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 ENPP3 내부 서열 유래 펩타이드로 면역화됨. 세포막 및 분비 단백질 검출에 적합하며, 사람, 생쥐, 랫트에 반응.
- 카탈로그번호
- ES4004-xxxxx (2개 옵션)
- 판매단위
- pk
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CD203c rabbit pAb
제품 개요
CD203c 단백질(ENPP3)을 인식하는 토끼 폴리클로날 항체입니다. 세포막 및 분비 단백질의 검출에 사용되며, 다양한 종(인간, 생쥐, 랫트)에 반응합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CD203c rabbit pAb |
| Alternative Names | ENPP3; PDNP3; Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; E-NPP 3; Phosphodiesterase I beta; PD-Ibeta; Phosphodiesterase I/nucleotide pyrophosphatase 3; CD203c |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000; IHC-p: 1/100–1/300; ELISA: 1/20000 (other applications not yet tested) |
| Immunogen | Synthesized peptide derived from the internal region of human ENPP3 (AA range: 281–330) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 100 kDa |
| GeneID (Human) | 5169 |
| Human Swiss-Prot No. | O14638 |
| Species Reactivity | Human; Mouse; Rat |
세포 내 위치
Cell membrane; Single-pass type II membrane protein.
Apical cell membrane; Single-pass type II membrane protein.
Secreted.
Detected at the cell surface of basophils (PubMed:11342463).
Detected at the apical plasma membrane of bile duct cells (PubMed:15072822).
Located to the apical surface in intestinal and kidney epithelial cells.
Secreted in serum and in the lumen of epithelial cells.
Background
The protein encoded by this gene belongs to a series of ectoenzymes involved in the hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins.
Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver.
The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells.
Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. (provided by RefSeq, Oct 2015)
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