Thermo Fisher Scientific FIP1 Polyclonal Antibody
Thermo Fisher Scientific의 FIP1 Polyclonal Antibody는 인간 FIP1L1 단백질을 인식하는 토끼 유래 IgG 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 4°C에서 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A301462A
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 544 and 594 of human factor interacting with PAP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex, which plays a key role in pre-mRNA 3'-end formation. It recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase and other factors to promote cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition by binding to U-rich RNA sequence elements surrounding the poly(A) site. It may act to tether poly(A) polymerase to the CPSF complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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