Thermo Fisher Scientific VAMP1 Monoclonal Antibody (SP10)
VAMP1 단백질을 인식하는 Mouse IgM 단일클론 항체로, Western blot 및 동결절편 면역조직화학에 적합합니다. 인간, 마우스, 소에 반응하며, 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SP10 |
| Immunogen | Synaptic immunoprecipitate (crude) from human brain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | IgM |
| Storage Buffer | 10 mM HEPES, pH 7.5, with 100 µg/mL BSA, 50% glycerol, 150 mM NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942674 |
Product Specific Information
This antibody is specific for endogenous levels of the ~16 kDa synaptobrevin. It has been demonstrated to work in immunohistochemistry on formalin-fixed, vibratome sections, but not on paraffin sections.
Target Information
Synaptobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane.
The protein encoded by this gene belongs to the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, though the full-length nature of some variants has not been defined.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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