Thermo Fisher Scientific CASC3 Polyclonal Antibody
Thermo Fisher Scientific의 CASC3 Polyclonal Antibody는 인간 CASC3 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 용액에 40% 글리세롤과 0.05% sodium azide를 포함합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:1,000
- Publications: [References not provided]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human cancer susceptibility candidate 3 (CASC3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635824 |
Product Specific Information
The antibody detects endogenous levels of total CASC3 protein.
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator. The 20S core has four rings of 28 non-identical subunits (two rings of 7 alpha and two rings of 7 beta subunits). The 19S regulator consists of a base with 6 ATPase subunits and 2 non-ATPase subunits, and a lid containing up to 10 non-ATPase subunits. Proteasomes are abundant in eukaryotic cells and cleave peptides via an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome, a modified form, processes class I MHC peptides and includes the 11S regulator (PA28), replacing the 19S regulator. This gene encodes the gamma subunit of the 11S regulator, forming a homohexameric ring. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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