
Thermo Fisher Scientific CENPJ Polyclonal Antibody
Human CENPJ 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 저장용액에 40% 글리세롤 포함. 세포 분열 및 중심체 관련 연구에 활용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human centromere protein J |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635830 |
Product Specific Information
The antibody detects endogenous levels of total CENPJ protein.
Target Information
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in maintaining centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. It can function as a transcriptional coactivator in the Stat5 signaling pathway and as a coactivator of NF-kappaB-mediated transcription, likely via interaction with p300/CREB-binding protein.
Mutations in this gene are associated with primary autosomal recessive microcephaly, characterized by severely reduced brain size and mental retardation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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