Thermo Fisher Scientific CENPJ Polyclonal Antibody

Applications

• Immunohistochemistry (Paraffin) (IHC (P))
  Tested Dilution: 1:25–1:100

Product Specifications

Product Specific Information

The antibody detects endogenous levels of total CENPJ protein.

Target Information

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in maintaining centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. It can function as a transcriptional coactivator in the Stat5 signaling pathway and as a coactivator of NF-kappaB-mediated transcription, likely via interaction with p300/CREB-binding protein.
Mutations in this gene are associated with primary autosomal recessive microcephaly, characterized by severely reduced brain size and mental retardation.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.