Thermo Fisher Scientific RHBDD1 Polyclonal Antibody
RHBDD1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 IHC(Paraffin)에서 검증됨. 인간 시료 반응성, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RHBDD1. Recombinant protein control fragment (Product #RP-90982). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646524 |
Product Specific Information
Immunogen sequence:
PLKKIMEACA GGFSSSVGYP GRQYYFNSSG SSGYQDYYPH GRPDHYEEAP RNYDTYTAGL SEEEQLERAL QASLWDRGNT RNSPPPYGFH LSPEEMRRQR LHRFD
Sequence identity:
- Mouse: 70%
- Rat: 73%
Target Information
The Rhomboid family of proteins comprises conserved membrane serine proteases involved in growth and development. RHBDD1 is highly expressed in the testis and participates in the cleavage of BIK, a proapoptotic Bcl-2 family member. Overexpression or RNAi-mediated suppression of RHBDD1 in 293 cells modulates BIK-mediated apoptosis. In GC-1 spermatogonia cells, RHBDD1 suppression leads to loss of survival and differentiation capacity, suggesting its role in mammalian spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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