Thermo Fisher Scientific GlyT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunohistochemistry (Frozen) (IHC (F))

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SLC6A9. Recombinant protein control fragment (Product #RP-90688). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GlyT1,uniProtId:P48067-1,ncbiNodeId:9606,antigenRange:219-285,antigenLength:706,antigenImageFileName:PA5-53103_GlyT1_P48067-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53103_GlyT1_P48067-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647554

Product Specific Information

Immunogen sequence: YCNNPWNTHD CAGVLDASNL TNGSRPAALP SNLSHLLNHS LQRTSPSEEY WRLYVLKLSD DIGNFGE

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 88%.

Target Information

Slc6a9 is a glycine transporter (GlyTs) that belong to a family of high affinity Na+- and Cl-dependent neurotransmitter transporters proteins. There are two subtypes of glycine transporters; GlyT1 (Slc6a9) and GlyT2. Slc6a9 are predominantly located on glia within caudal brain areas. The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by the Slc6a9 gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. Diseases associated with SLC6A9 include Glycine Encephalopathy With Normal Serum Glycine and Infantile Glycine Encephalopathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.