Thermo Fisher Scientific GlyT1 Polyclonal Antibody
Human GlyT1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P), IHC(F), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. 신경전달물질 글라이신 수송 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunohistochemistry (Frozen) (IHC (F)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SLC6A9. Recombinant protein control fragment (Product # RP-90688) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647554 |
Product Specific Information
Immunogen sequence:
YCNNPWNTHD CAGVLDASNL TNGSRPAALP SNLSHLLNHS LQRTSPSEEY WRLYVLKLSD DIGNFGE
Sequence identity:
- Mouse: 91%
- Rat: 88%
Target Information
Slc6a9 (GlyT1) is a glycine transporter belonging to the family of high-affinity Na⁺- and Cl⁻-dependent neurotransmitter transporters. Two subtypes exist: GlyT1 (Slc6a9) and GlyT2. Slc6a9 is predominantly located on glial cells within caudal brain regions. Glycine acts as an inhibitory neurotransmitter in the central nervous system. The SLC6A9 gene encodes one of two transporters that terminate glycine signaling by removing it from the synaptic cleft.
Associated diseases:
- Glycine Encephalopathy With Normal Serum Glycine
- Infantile Glycine Encephalopathy
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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