Thermo Fisher Scientific CHIA Monoclonal Antibody (OTI3H4), TrueMAB
CHIA 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot과 IHC(Paraffin) 실험에 적합합니다. 인간 시료 반응성이 있으며, Lyophilized 형태로 제공됩니다. 항체 재구성 및 결합 실험에 적합한 고순도 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H4 |
| Immunogen | Full length human recombinant protein of CHIA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
CHIA degrades chitin and chitotriose and may participate in defense against nematodes and other pathogens.
Three isoforms are produced by alternative splicing.
CHIA is induced via a Th2-specific, interleukin-13-mediated pathway in epithelial cells and macrophages.
It may serve as a key mediator of IL13-induced responses in Th2-dominated disorders such as asthma.
CHIA hydrolyzes N-acetyl-β-D-glucosaminide 1,4-β-linkages in chitin and chitodextrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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