
Thermo Fisher Scientific Cathepsin C Polyclonal Antibody
Mouse 및 Rat에 반응하는 Goat Polyclonal Cathepsin C 항체로, WB 및 IHC(F)에 사용 가능. 항원 친화 크로마토그래피로 정제된 Lyophilized 형태. PBS 및 trehalose buffer로 보관하며, 연구용으로만 사용.
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- PA547049
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Applications
Western Blot (WB)
- Tested Dilution: 0.25–1 µg/mL
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: 5–15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse Cathepsin C/DPPI (Asp25–Leu462) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608218 |
Product Specific Information
- In direct ELISAs, approximately 15% cross-reactivity with recombinant human Cathepsin C is observed.
- Less than 1% cross-reactivity with recombinant mouse Cathepsin A, B, D, H, and X/Z/P.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Cathepsin C (DPPI, dipeptidyl aminopeptidase I) is a tetrameric lysosomal cysteine peptidase of the papain family. It plays a role in intracellular protein degradation and precursor processing, participating in cell growth, neuraminidase activation, and platelet factor XIII activation.
Highly expressed in spleen, kidney, cytotoxic lymphocytes, and myeloid cells, Cathepsin C localizes to secretory granules. It is synthesized as a proenzyme and processed into two chains forming the mature enzyme.
Enzymatic activity requires halide ions (chloride) and thiols for full function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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