Thermo Fisher Scientific MAP2K4 Monoclonal Antibody (5H4)
MAP2K4 단백질을 인식하는 Thermo Fisher의 mouse monoclonal antibody(5H4). Western blot, IHC, Flow cytometry, ELISA에 사용 가능. Human 시료에 반응하며, 비결합형 액상 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5H4 |
| Immunogen | Purified recombinant fragment of human MAP2K4 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155386 |
Product Specific Information
MA5-15811 targets MAP2K4 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples.
The immunogen is a purified recombinant fragment of human MAP2K4 expressed in E. coli.
This antibody detects MAP2K4 with a predicted molecular weight of approximately 42 kDa.
Target Information
MAP2K4 (also known as MEK4 or MKK4) is a serine/threonine kinase belonging to the STE7 family. It phosphorylates and activates JNK1, JNK2, and p38 MAP kinases. MAP2K4 primarily phosphorylates the tyrosine residue of JNKs and is involved in various physiological and pathological processes, including responses to cellular stress and inflammatory cytokines.
Loss-of-function mutations in MAP2K4 have been identified in lung and pancreatic tumors, while pro-oncogenic roles have also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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