Thermo Fisher Scientific MEK6 Monoclonal Antibody (3H12B9)
Human 및 Mouse 시료에서 MAP2K6 단백질을 검출하는 MEK6 단클론 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용 가능. 비결합형 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장. 연구용으로만 사용.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H12B9 |
| Immunogen | Purified recombinant fragment of human MAP2K6 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11155010 |
Product Specific Information
MA5-15809 targets MAP2K6 in indirect ELISA, IHC, and WB applications, showing reactivity with human and mouse samples.
The immunogen is a purified recombinant fragment of human MAP2K6 expressed in E. coli.
MA5-15809 detects MAP2K6 with a predicted molecular weight of approximately 38 kDa.
Target Information
MKK6 (MEK6, MAP2K6) is a member of the dual specificity protein kinase family, functioning as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals.
This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of the p38 MAP kinase-mediated signal transduction pathway, it is involved in cellular processes such as stress-induced cell cycle arrest, transcription activation, and apoptosis.
Tissue Specificity:
- Isoform 2: Expressed only in skeletal muscle
- Isoform 1: Found in skeletal muscle, heart, and to a lesser extent in liver or pancreas
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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