Thermo Fisher Scientific SH3BP1 Polyclonal Antibody
SH3BP1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 Polyclonal 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 인간 시료에 반응합니다. 합성 펩타이드로 면역화되었으며, 0.5 mg/mL 농도의 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.3 µg/mL | – |
| Immunocytochemistry (ICC/IF) | Assay-dependent | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (PQPRPRSLASETN) corresponding to the C-terminus amino acids of SH3BP1 (aa 689–701) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982350 |
Product Specific Information
This antibody is tested in Peptide ELISA with an antibody detection limit dilution of 16,000.
Target Information
SH3BP1 binds differentially to the SH3 domains of certain proteins in signal transduction pathways. It preferentially binds to ABL1 proto-oncogene, SRC, and GRB2. Exhibits GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. Inhibits PDGF-induced membrane ruffling mediated by Rac.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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