Thermo Fisher Scientific CD44v4/5 (Marker of Tumor Metastasis) Monoclonal Antibody (3D2)
CD44v4/5 단백질을 인식하는 인간 반응성 단클론 항체로, 종양 전이 마커 연구에 적합. Western blot, IHC, Flow cytometry 등 다양한 응용 가능. Mouse IgG1, kappa 형이며, PBS 용액에 보존된 비결합형 항체. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CD44v4/5 (Marker of Tumor Metastasis) Monoclonal Antibody (3D2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D2 |
| Immunogen | Recombinant human full-length CD44v3–10 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This antibody recognizes an epitope encoded by exon v9 on the variant portion of human CD44.
CD44 belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial, and hematopoietic tissues.
The CD44 gene contains 20 exons, of which 10 encode the basic CD44 (H-CAM) molecule. The remaining 10 exons (v1–v10) are expressed through alternative splicing of nuclear RNA.
Expression of specific CD44 splice variants has been associated with metastasis in certain human malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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