Thermo Fisher Scientific CD44v4/5 (Marker of Tumor Metastasis) Monoclonal Antibody (3D2)
CD44v4/5 단백질을 인식하는 종양 전이 마커 단클론 항체. Western blot, IHC, Flow Cytometry 등 다양한 응용 가능. 인간 CD44 변이 영역 특이적 인식. 단백질 A/G 정제, PBS 버퍼 보존, 연구용 전용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D2 |
| Immunogen | Recombinant human full-length CD44v3-10 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This antibody recognizes an epitope encoded by exon v9 on the variant portion of human CD44.
CD44 belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial, and hemopoietic tissues.
The CD44 gene has 20 exons, of which 10 encode the basic CD44 (H-CAM) molecule.
The additional 10 exons (v1–v10) are expressed through alternative splicing of nuclear RNA.
Expression of specific CD44 splice variants has been associated with metastasis in certain human malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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