Thermo Fisher Scientific NKX2 Monoclonal Antibody (OTI3F3), TrueMAB

Thermo Fisher Scientific NKX2 Monoclonal Antibody (OTI3F3), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes a protein originally identified as a thyroid-specific transcription factor. It binds to the thyroglobulin promoter and regulates expression of thyroid-specific genes, as well as genes involved in morphogenesis.
Mutations and deletions in this gene are linked to benign hereditary chorea, choreoathetosis, congenital hypothyroidism, neonatal respiratory distress, and may be associated with thyroid cancer.
Multiple transcript variants encoding different isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.