Thermo Fisher Scientific Infliximab Chimeric Recombinant Human Monoclonal Antibody (cA2 (Infliximab))
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Infliximab 키메라 재조합 인간 단클론 항체로 TNF-α에 결합하여 생물학적 활성을 중화함. Western blot, ELISA, Flow cytometry 등 다양한 어플리케이션에 사용 가능. HEK293 세포에서 발현된 IgG1, kappa 항체. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1.5 µg/mL | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
| ELISA (ELISA) | Assay-dependent | - |
| Functional Assay (Functional) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | cA2 (Infliximab) |
| Immunogen | Purified recombinant human TNF (rTNF) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074246 |
Product Specific Information
- Specificity: Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.
Target Information
Infliximab (Remicade) is a chimeric monoclonal IgG1 antibody that binds to TNF-alpha, a key proinflammatory cytokine involved in chronic inflammatory diseases. It acts as a TNF-alpha blocker, disrupting the interaction between TNF-alpha and its receptors.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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