Thermo Fisher Scientific Infliximab Chimeric Recombinant Human Monoclonal Antibody (cA2 (Infliximab))

Applications

Tested Dilution

Publications

Western Blot (WB)

1.5 µg/mL

-

Flow Cytometry (Flow)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Functional Assay (Functional)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Human / IgG1, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

cA2 (Infliximab)

Immunogen

Purified recombinant human TNF (rTNF).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3074246

Product Specific Information

Specificity: Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.

Target Information

Infliximab with the brand name of Remicade, is a chimeric monoclonal IgG1 antibody. It binds to TNF-alpha, which is a key proinflammatory cytokine involved in chronic inflammatory diseases. Infliximab functions as TNF-alpha blocker to disrupt the interaction of TNF-alpha with its receptors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.