Thermo Fisher Scientific CSF2 Monoclonal Antibody (OTI6H1), TrueMAB

Thermo Fisher Scientific CSF2 Monoclonal Antibody (OTI6H1), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form exists as a homodimer in the extracellular space.
This gene is located in a cluster on chromosome region 5q31, associated with 5q- syndrome and acute myelogenous leukemia. Related genes include IL-4, IL-5, and IL-13.
GM-CSF promotes tissue inflammation; elevated levels have been observed in SARS-CoV-2 patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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