Thermo Fisher Scientific CSF2 Monoclonal Antibody (OTI6H1), TrueMAB
인간 CSF2(GM-CSF) 단백질을 인식하는 단클론 항체로 Western blot에 최적화됨. 항원은 E. coli에서 생산된 인간 CSF2 아미노산 18–144 영역. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험에 적합. 연구용 전용 제품.
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Thermo Fisher Scientific CSF2 Monoclonal Antibody (OTI6H1), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6H1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18–144 of human CSF2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form exists as a homodimer in the extracellular space.
This gene is located in a cluster on chromosome region 5q31, associated with 5q- syndrome and acute myelogenous leukemia. Related genes include IL-4, IL-5, and IL-13.
GM-CSF promotes tissue inflammation; elevated levels have been observed in SARS-CoV-2 patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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