Thermo Fisher Scientific NAPSA Monoclonal Antibody (OTI2F11), TrueMAB
Human NAPSA 단백질(aa 64-244)에 특이적인 Mouse Monoclonal Antibody. IHC(P) 검증 완료. 동결건조 형태로 제공되며, 재구성 시 1 mg/mL 농도 권장. 폐 및 신장 조직 연구 및 암 진단용 바이오마커 연구에 적합. 연구용으로만 사용 가능.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 64–244 of human NAPSA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Napsin 1 is an aspartic protease primarily expressed in the lung, with additional expression in the kidney and metastatic carcinomas. It processes surfactant protein B in pulmonary and renal tissues and is dysregulated during carcinogenesis.
Napsin evaluation is useful for identifying various cancers and distinguishing primary tumors from metastases. When combined with thyroid transcription factor analysis, Napsin serves as a specific biomarker for carcinoma differentiation. It is also implicated in pulmonary alveolar proteinosis and protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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