Thermo Fisher Scientific CCL5 (RANTES) Polyclonal Antibody, Biotin, PeproTech

Thermo Fisher Scientific CCL5 (RANTES) Polyclonal Antibody, Biotin, PeproTech

Applications and Tested Dilution

Product Specifications

Product Specific Information

• AA Sequence of recombinant protein:
  SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS.

• Preparation:
  Produced from sera of rabbits immunized with highly pure Recombinant Murine RANTES (CCL5). Purified by affinity chromatography and biotinylated.

• Sandwich ELISA:
  For detection of Murine RANTES (CCL5), use 0.25–1.0 µg/mL of antibody (100 µL/well). In combination with PeproTech Polyclonal Anti-Murine RANTES (CCL5) (500-P118) as capture antibody, detects ≥0.2–0.4 ng/well of Recombinant Murine RANTES (CCL5).

• Western Blot:
  Detects mRANTES at 0.1–0.2 µg/mL. Detection limit for Recombinant mRANTES is 1.5–3.0 ng/lane under reducing or non-reducing conditions.

• Package Information:
  500-P118BT-1MG is provided as 2 × 500 µg.

Target Information

CCL5 (RANTES) is a chemokine gene located on chromosome 17q. It encodes a protein that functions as a chemoattractant for monocytes, memory T helper cells, and eosinophils. CCL5 activates eosinophils, induces histamine release from basophils, and serves as a natural ligand for CCR5, suppressing replication of HIV-1 R5 strains. It plays roles in immunoregulatory and inflammatory processes. Alternative splicing produces multiple isoforms. Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.

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