Thermo Fisher Scientific GSTP1 Recombinant Rabbit Monoclonal Antibody (RM347)
GSTP1 단백질을 인식하는 재조합 토끼 단클론 항체로, 높은 특이성과 재현성을 제공. WB, IHC, ICC/IF 등 다양한 실험에 적합. HEK293 세포 발현 시스템으로 생산되어 로트 간 일관성 우수. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:20,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RM347 |
| Immunogen | A peptide corresponding to the C-terminus of human GST3/GST-pi |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2744966 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
Glutathione S-transferases (GSTs) are a family of enzymes crucial for detoxification by catalyzing conjugation of hydrophobic and electrophilic compounds with reduced glutathione. Based on biochemical, immunologic, and structural properties, soluble GSTs are categorized into four main classes: alpha, mu, pi, and theta.
This GST family member, GSTP1, is a polymorphic gene encoding functionally distinct variants that play roles in xenobiotic metabolism and may influence susceptibility to cancer and other diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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