Thermo Fisher Scientific SEC62 Recombinant Rabbit Monoclonal Antibody (PSH0-25)
Recombinant rabbit monoclonal antibody targeting human SEC62 protein. Validated for Western blot applications. High specificity with multiple species reactivity (human, mouse, rat). Supplied as liquid form with 1 mg/mL concentration and Protein A purif...
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Applications
- Western Blot (WB)
Tested Dilution: 1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PSH0-25 |
| Immunogen | Synthetic peptide within human SEC62 aa 1–50/399 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093906 |
Product Specific Information
- Positive Control: Hela, K562, SH-SY5Y, HepG2, 293T, Jurkat, NIH/3T3, PC-12 cell lysates; mouse liver/brain tissue lysates; rat liver tissue lysate; human liver tissue lysate
- Predicted Band Size: 46 kDa
- Subcellular Location: Endoplasmic reticulum membrane
Target Information
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
[provided by RefSeq]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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