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Thermo Fisher Scientific CDC6 Recombinant Rabbit Monoclonal Antibody (JE59-52)
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CDC6 단백질을 인식하는 재조합 토끼 단클론 항체로, 인산화 Ser54 주변 펩타이드로부터 유래함. Western blot 및 IHC에 적합하며, 인간 시료 반응성. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적 액상 형태.
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마지막 업데이트 2025. 07. 29. 오전 09:19
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Thermo Fisher Scientific MA550795 CDC6 Recombinant Rabbit Monoclonal Antibody (JE59-52) 100 ul pk판매 단위 pk ·
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725,400원VAT 포함 797,940원
Thermo Fisher Scientific · Thermo Fisher Scientific CDC6 Recombinant Rabbit Monoclonal Antibody (JE59-52)
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE59-52 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Ser54 of Human Cdc6 (aa 41–90/560) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092989 |
Product Specific Information
- Positive control: HeLa cell lysate, HepG2 cell lysate, human striated muscle tissue, human testis muscle tissue
- Predicted band size: 63 kDa
- Subcellular Location: Nucleus, Cytoplasm
Target Information
The CDC6 protein is homologous to Saccharomyces cerevisiae Cdc6, essential for initiating DNA replication. It regulates early DNA replication steps, localizing to the nucleus during G1 phase and translocating to the cytoplasm at the start of S phase. Its movement is controlled by phosphorylation through Cdks, and transcription is regulated by E2F proteins in response to mitogenic signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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