Thermo Fisher Scientific FASN Polyclonal Antibody
Thermo Fisher Scientific의 FASN Polyclonal Antibody는 사람 FASN 단백질을 인식하는 토끼 IgG 항체로, Western blot, IHC, ELISA, IP 등에 적합합니다. 고순도 친화 크로마토그래피 정제 방식으로 제조되었으며, PBS/glycerol 완충액에 보관됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:100 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 2212–2511 of human FASN (NP_0040954) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804149 |
Product Specific Information
Immunogen sequence:
QQQTQLNLRS LLVNPEGPTL MRLNSVQSSE RPLFLVHPIE GSTTVFHSLA SRLSIPTYGL QCTRAAPLDS IHSLAAYYID CIRQVQPEGP YRVAGYSYGA CVAFEMCSQL QAQQSPAPTH NSLFLFDGSP TYVLAYTQSY RAKLTPGCEA EAETEAICFF VQQFTDMEHN RVLEALLPLK GLEERVAAAV DLIIKSHQGL DRQELSFAAR SFYYKLRAAE QYTPKAKYHG NVMLLRAKTG GAYGEDLGAD YNLSQVCDGK VSVHVIEGDH RTLLEGSGLE SIISIIHSSL AEPRVSVREG
Positive Samples: H460
Cellular Location: Cytoplasm, Melanosome
Target Information
Fatty acid synthase (FASN) is a multifunctional enzyme responsible for catalyzing the synthesis of palmitate from acetyl-CoA and malonyl-CoA in the presence of NADPH, producing long-chain saturated fatty acids. In certain cancer cell lines, FASN has been reported to form a fusion with estrogen receptor-alpha (ER-α), where the N-terminus of FAS is fused in-frame with the C-terminus of ER-α.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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