Thermo Fisher Scientific CD19 Polyclonal Antibody
CD19 단백질을 표적하는 Rabbit Polyclonal Antibody로, 인간 및 마우스 시료에 반응. Western blot과 Immunocytochemistry에 적합. 고순도 Affinity chromatography 정제, PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CD19 (Accession P15391), corresponding to amino acid residues G505–T555 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899605 |
Product Specific Information
Antibody detects endogenous levels of total CD19.
Target Information
CD19 is a member of the immunoglobulin superfamily and has two Ig-like domains. It is expressed on 100% of peripheral B cells and also found on certain myeloid leukemia cells. CD19 serves as a signal-amplifying coreceptor for the B cell receptor (BCR) and can also signal independently. It regulates normal and malignant B cell proliferation. Mutation of the CD19 gene results in hypogammaglobulinemia, while overexpression causes B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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