Thermo Fisher Scientific BIRC3 Monoclonal Antibody (OTI2G7), TrueMAB
인간 BIRC3 단백질을 타겟으로 하는 Mouse IgG1 단클론 항체로, Western blot에 최적화됨. 무보존제 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 세포자멸 억제 관련 연구용으로 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 255–529 of human BIRC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The protein encoded by BIRC3 is a member of a family that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, likely interfering with activation of ICE-like proteases.
It inhibits apoptosis induced by serum deprivation but not that caused by menadione exposure.
The amino acid sequence includes three baculovirus IAP repeat domains and a ring finger domain.
Transcript variants encoding the same isoform have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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