Thermo Fisher Scientific BIRC3 Monoclonal Antibody (OTI2B7), TrueMAB
인간 BIRC3 단백질을 인식하는 단클론 항체로 Western blot에 적합. E. coli에서 생산된 재조합 단백질을 면역원으로 사용. 동결건조 형태로 제공되며, PBS 완충액과 trehalose 포함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 255–529 of human BIRC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The BIRC3 gene encodes a protein that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, likely interfering with activation of ICE-like proteases.
This protein inhibits apoptosis induced by serum deprivation but not that caused by menadione exposure. It contains three baculovirus IAP repeat domains and a RING finger domain. Transcript variants encoding the same isoform have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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