Thermo Fisher Scientific SLC39A5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human SLC39A5. Recombinant protein control fragment (Product #RP-91280). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC39A5,uniProtId:Q6ZMH5-1,ncbiNodeId:9606,antigenRange:49-179,antigenLength:540,antigenImageFileName:PA5-110838_SLC39A5_Q6ZMH5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110838_SLC39A5_Q6ZMH5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856249

Product Specific Information

Immunogen sequence: ENGTLTAGGL ARLLHSLGLG RVQGLRLGQH GPLTGRAASP AADNSTHRPQ NPELSVDVWA GMPLGPSGWG DLEESKAPHL PRGPAPSGLD LLHRLLLLDH SLADHLNEDC LNGSQLLVNF GLSPAAPLTP R

Target Information

The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.