Thermo Fisher Scientific SLC39A5 Polyclonal Antibody
SLC39A5 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인체 시료에 반응합니다. ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며, 연구용으로만 사용 가능합니다.
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- PA5110838
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human SLC39A5. Recombinant protein control fragment (Product # RP-91280) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856249 |
Product Specific Information
Immunogen sequence:
ENGTLTAGGL ARLLHSLGLG RVQGLRLGQH GPLTGRAASP AADNSTHRPQ NPELSVDVWA GMPLGPSGWG DLEESKAPHL PRGPAPSGLD LLHRLLLLDH SLADHLNEDC LNGSQLLVNF GLSPAAPLTP R
Target Information
The zinc transporter ZIP5 (SLC39A5) is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in growth, development, and differentiation. ZIP5 is closely related to ZIP4 and is found in many of the same tissues, including intestine, pancreas, liver, and kidney. Unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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