Thermo Fisher Scientific ATG4A Polyclonal Antibody
Human ATG4A 단백질을 인식하는 Sheep 유래 Polyclonal 항체로, Western blot과 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 trehalose buffer에 동결건조 형태로 제공. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Sf21-derived recombinant human ATG4A (Glu2–Val398) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606322 |
Product Specific Information
- In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human ATG4GB is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. It is essential for cell homeostasis and remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced autophagy levels have been observed in certain tumors, suggesting a role in regulating unregulated cell growth related to cancer.
This gene encodes a member of the autophagin protein family and is also classified as part of the C-54 family of cysteine proteases. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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