Thermo Fisher Scientific TXNL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TXNL1. Recombinant protein control fragment (Product #RP-101856). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TXNL1,uniProtId:O43396-1,ncbiNodeId:9606,antigenRange:137-284,antigenLength:289,antigenImageFileName:PA5-51748_TXNL1_O43396-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51748_TXNL1_O43396-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649146

Product Specific Information

Immunogen sequence: CLNESDEHGF DNCLRKDTTF LESDCDEQLL ITVAFNQPVK LYSMKFQGPD NGQGPKYVKI FINLPRSMDF EEAERSEPTQ ALELTEDDIK EDGIVPLRYV KFQNVNSVTI FVQSNQGEEE TTRISYFTFI GTPVQATNMN DFKRVVGK

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Target Information

Thioredoxins are a group of small redox active proteins possessing a conserved active site sequence. TrxL (Thioredoxin like protein 1) has 2 distinct domains: an N terminal domain, which is 43% identical to human TXN, and a C terminal domain, which shows no homology to other proteins in the sequence databases. The active site sequence, located within the N terminal domain, is that of a thioredoxin like protein; compared to the active site sequence of TXN, it has a single amino acid substitution. Unlike other thioredoxin like proteins, TrxL does not serve as a substrate for thioredoxin reductase in an insulin assay.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.