Thermo Fisher Scientific TXNL1 Polyclonal Antibody
TXNL1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TXNL1. Recombinant protein control fragment (Product #RP-101856). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649146 |
Product Specific Information
Immunogen sequence:
CLNESDEHGF DNCLRKDTTF LESDCDEQLL ITVAFNQPVK LYSMKFQGPD NGQGPKYVKI FINLPRSMDF EEAERSEPTQ ALELTEDDIK EDGIVPLRYV KFQNVNSVTI FVQSNQGEEE TTRISYFTFI GTPVQATNMN DFKRVVGK
Highest antigen sequence identity to the following orthologs:
- Mouse: 98%
- Rat: 98%
Target Information
Thioredoxins are a group of small redox-active proteins possessing a conserved active site sequence.
TrxL (Thioredoxin-like protein 1) has two distinct domains:
- N-terminal domain: 43% identical to human TXN
- C-terminal domain: no homology to other proteins in sequence databases
The active site sequence, located within the N-terminal domain, resembles that of a thioredoxin-like protein with a single amino acid substitution compared to TXN.
Unlike other thioredoxin-like proteins, TrxL does not serve as a substrate for thioredoxin reductase in an insulin assay.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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