Thermo Fisher Scientific CDKL5 Polyclonal Antibody
Rabbit polyclonal antibody against human CDKL5 protein. Recognizes serine/threonine kinase involved in neuronal development. Suitable for research use in studies of Rett syndrome and X-linked infantile spasms. Supplied as liquid, 0.2 mg/mL, store at 4°...
- 카탈로그번호
- PA551752
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CDKL5 Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CDKL5 (amino acids 636–758) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639615 |
Product Specific Information
Immunogen sequence:
AARANSLQLL SPQPGEQLPP EMTVARSSVK ETSREGTSSF HTRQKSEGGV YHDPHSDDGT APKENRHLYN DPVPRRVGSF YRVPSPRPDN SFHENNVSTR VSSLPSESSS GTNHSKRQPA FDP
Sequence identity to orthologs:
- Mouse: 96%
- Rat: 97%
Target Information
CDKL5 (Cyclin-dependent kinase-like 5), also known as STK9, is a serine/threonine kinase associated with X-linked infantile spasm syndrome (ISSX), X-linked West syndrome, and Rett syndrome (RTT).
CDKL5 regulates nuclear speckle morphology by modulating phosphorylation of splicing regulatory proteins, influencing pre-mRNA processing and splicing factor dynamics.
Mutations in CDKL5 are a major cause of infantile spasms and early epileptic seizures, particularly in female patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.