Thermo Fisher Scientific SLC15A1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SLC15A1. Recombinant protein control fragment (Product #RP-101759). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC15A1,uniProtId:P46059-1,ncbiNodeId:9606,antigenRange:383-515,antigenLength:708,antigenImageFileName:PA5-51747_SLC15A1_P46059-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51747_SLC15A1_P46059-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647357

Product Specific Information

Immunogen sequence: DKTLPVFPKG NEVQIKVLNI GNNTMNISLP GEMVTLGPMS QTNAFMTFDV NKLTRINISS PGSPVTAVTD DFKQGQRHTL LVWAPNHYQV VKDGLNQKPE KGENGIRFVN TFNELITITM SGKVYANISS YNA

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 72%.

Target Information

In mammalian small intestine, the proton-coupled peptide transporter (PEPT) is responsible for the absorption of small peptides arising from digestion of dietary proteins. PEPT1, a hydrogen ion/peptide cotransporter, transports dipeptides and tripeptides, but not free amino acids or peptides with more than three amino acid residues. Its driving force for uphill transport requires proton binding and the presence of an inside-negative membrane potential. PEPT1 is 708 amino acid protein that contains 12 putative membrane-spanning domains. PEPT1 is expressed in Caco-2 cells. PEPT1 seems to play important roles in nutritional and pharmacological therapies. The mammalian kidney expresses a proton-coupled peptide transporter, PEPT2, that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.