Thermo Fisher Scientific CD271 (NGF Receptor) Recombinant Rabbit Monoclonal Antibody (SA39-02)
CD271 (NGF Receptor) 표적의 재조합 토끼 단클론 항체로 높은 특이성과 민감도를 제공. WB, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합. 로트 간 일관성 및 동물 유래 성분 없는 포뮬레이션. 신경계 발달 및 재생 연구에 활용 가능.
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Thermo Fisher Scientific CD271 (NGF Receptor) Recombinant Rabbit Monoclonal Antibody (SA39-02)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:5,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 | - |
| Flow Cytometry (Flow) | 1:200 | - |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SA39-02 |
| Immunogen | Synthetic peptide within Human p75 NGF Receptor aa 345–394 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809262 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal production candidates.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Neurotrophic factors regulate survival, differentiation, and maintenance of neurons in both peripheral and central nervous systems, as well as other neural crest-derived cells. Developing sympathetic neurons depend on nerve growth factor (NGF) during target competition in vivo.
Antibodies specific to NGFR p75 are valuable tools for detecting and characterizing NGFR p75, aiding research on neural development, plasticity, and repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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