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Thermo Fisher Scientific Phospho-NEDD4L (Ser342) Polyclonal Antibody
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Phospho-NEDD4L (Ser342) 폴리클로날 항체로 인산화된 NEDD4L 단백질 검출에 적합. Western blot 및 IHC(P)에서 사용 가능. Rabbit IgG 유래 비결합 항체로 PBS/glycerol 용액 형태. 연구용으로만 사용.
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- pk
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마지막 업데이트 2025. 08. 01. 오후 06:08
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Thermo Fisher Scientific PA5105224 Phospho-NEDD4L (Ser342) Polyclonal Antibody 100 ul pk판매 단위 pk ·
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627,600원VAT 포함 690,360원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-NEDD4L (Ser342) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NEDD4L (Accession Q96PU5), corresponding to amino acid residues around phosphorylated Ser342. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816697 |
Product Specific Information
This antibody detects endogenous levels of NEDD4L only when phosphorylated at Ser342.
Target Information
NEDD4L is an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers it to target substrates. It inhibits TGF-beta signaling by promoting ubiquitination and degradation of SMAD2 and TGFR1. NEDD4L also regulates plasma membrane channel internalization and degradation, including ENaC, Nav channels, Kv1.3, EAAT1, and CLC5, as well as SGK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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