Thermo Fisher Scientific VIM Monoclonal Antibody (OTI5B9), TrueMAB
Human Vimentin 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot에 적합. TrueMAB 포맷으로 높은 특이성과 재현성을 제공. 1 mg/mL 농도의 액상 형태로 안정적이며, PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B9 |
| Immunogen | Human recombinant protein fragment (aa 210–466 of human VIM) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in intracellular transport of proteins between the nucleus and plasma membrane. Vimentin, along with desmin, is expressed during early cellular development and later replaced by tissue-specific IFPs. It plays a role in steroid synthesis by acting as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin leads to cytoskeletal changes facilitating cholesterol transport to mitochondria, enhancing steroid synthesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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