Thermo Fisher Scientific TYMP Monoclonal Antibody (OTI7B4), TrueMAB
TYMP 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공. PBS, BSA, 글리세롤 기반 버퍼에 보존되며, -20°C에서 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7B4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Thymidine phosphorylase (TP), also known as platelet-derived endothelial cell growth factor (PD-ECGF) or gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It functions as a chemotactic and mitogenic factor for endothelial cells and acts as a non-heparin-binding angiogenic factor in platelets. TYMP is also involved in the metabolic activation of fluoropyrimidines, cytotoxic drugs used in cancer therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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