Thermo Fisher Scientific KDEL Recombinant Rabbit Monoclonal Antibody (JB42-04)
KDEL 서열을 인식하는 재조합 토끼 단일클론 항체로, ER 단백질 표지에 사용됩니다. Western blot, IHC, ICC/IF, Flow cytometry 등에 적합하며, 다양한 종(인간, 마우스, 랫드)에 반응합니다. 고순도 Protein A 정제 및 안정한 액상 형태로 제공됩니다.
- 카탈로그번호
- MA534715
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific KDEL Recombinant Rabbit Monoclonal Antibody (JB42-04)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:400 |
| Immunocytochemistry (ICC/IF) | 1:400–1:800 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JB42-04 |
| Immunogen | Synthetic peptide CSEKDEL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848623 |
Product Specific Information
Positive Control:
Rat testis tissue, Mouse testis tissue, 293, HepG2, A549, 293T, rat epididymis tissue, human placenta tissue, human stomach cancer tissue, mouse small intestine tissue.
Target Information
The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins.
78 and 94 kDa glucose regulated proteins, GRP78 and GRP94 respectively, and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence.
The presence of carboxy-terminal KDEL appears to be necessary for ER retention and sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.