Thermo Fisher Scientific GRIK5 Monoclonal Antibody (4G5H8)
GRIK5 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody. Western blot 및 ELISA에 사용 가능하며, 단백질 정제는 Protein G 방식으로 수행됨. 액상 형태로 제공되며 장기 보관 시 -20°C 권장.
- 카탈로그번호
- MA531747
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G5H8 |
| Immunogen | Purified recombinant fragment of human GRIK5 (AA: extra 21–166) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787370 |
Product Specific Information
MA5-31747 has been tested in indirect ELISA.
Target Information
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes.
Grik5, also known as kainate-preferring glutamate receptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels.
Grik5 is highly homologous to the related ionotrophic glutamate receptor Grik4 (KA1). Like Grik4, Grik5 does not form homomeric channels, but instead forms heteromers with Grik2.
In Grik2- but not Grik1- mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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