Thermo Fisher Scientific mGluR3 Monoclonal Antibody (6H10C3)
mGluR3 단백질을 표적하는 Mouse monoclonal antibody. Western blot, IHC, Flow cytometry, ELISA 등 다양한 응용 가능. 고순도 Protein G 정제 및 PBS buffer에 0.05% sodium azide 함유. 연구용으로 4°C 또는 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6H10C3 |
| Immunogen | Purified recombinant fragment of human GRM3 (AA 433–576) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787372 |
Product Specific Information
MA5-31749 has been tested in indirect ELISA.
Target Information
Glutamate is the main excitatory neurotransmitter in the brain. It acts on ligand-gated receptor channels such as NMDA, AMPA, and kainate receptors involved in fast excitatory synaptic transmission. Additionally, glutamate regulates enzymes producing second messengers via metabotropic glutamate receptors (mGluRs) coupled to G-proteins.
Group I receptors (mGluR1a, mGluR5) stimulate phospholipase C, increasing phosphoinositide turnover and calcium release.
Group II and III receptors (including mGluR2 and mGluR3) inhibit adenylyl cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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