Thermo Fisher Scientific TRPM8 Polyclonal Antibody
TRPM8 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 냉각 감지 관련 연구에 유용합니다. 동결 건조 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장.
- 카탈로그번호
- OST00317W-100UL
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human TRPM8 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPM8.
Target Information
TRPM8 is a receptor-activated non-selective cation channel involved in detection of cool sensations, activated by cold temperatures below 25°C as well as compounds such as icilin, eucalyptol, and menthol. It is permeable to monovalent cations (Na⁺, K⁺, Cs⁺) and divalent cation (Ca²⁺).
Expression of TRPM8 is primarily found in prostate epithelial cells, with moderate mRNA levels in normal prostate tissue and elevated levels in prostate cancer. TRPM8 mRNA is also expressed in certain non-prostatic tumors (breast, colon, lung, skin), but rarely detected in corresponding normal tissues.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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