Thermo Fisher Scientific SCAMP5 Polyclonal Antibody
SCAMP5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 인간·마우스·랫트 반응성. 합성 펩타이드 항원 기반, 보존제 무첨가, 연구용 전용 제품.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 180–230 of rat SCAMP5 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in mouse and shares 95% identity with human.
- Specificity: SCAMP5.
Target Information
Secretory carrier membrane proteins (SCAMPs) are components of post-Golgi membranes involved in membrane trafficking.
In fibroblasts, SCAMPs are concentrated in compartments associated with recycling of cell surface receptors and endocytosis.
In neurons, SCAMPs are found in synaptic vesicles, secretion granules, and transporter vesicles.
SCAMPs have four central transmembrane regions and a cytoplasmic tail.
Of the five known SCAMPs, SCAMPs 1–3 contain N-terminal NPF repeats interacting with EH domain proteins involved in vesicle budding.
SCAMPs 4 and 5 lack NPF repeats. SCAMPs 1–4 are ubiquitously expressed, while SCAMP5 is detectable only in the brain and expressed late in development, coinciding with mature synapse formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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