Thermo Fisher Scientific TAF2 Monoclonal Antibody (OTI2A5), TrueMAB

Thermo Fisher Scientific TAF2 Monoclonal Antibody (OTI2A5), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.
TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors (TAFs). TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition, or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.
This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex and contributes to interactions at and downstream of the transcription initiation site, helping determine transcription complex response to activators.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.