Thermo Fisher Scientific p73 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 487-636 of human TP73 (NP_005418.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:p73,uniProtId:O15350-1,ncbiNodeId:9606,antigenRange:487-636,antigenLength:636,antigenImageFileName:PA5-120045_p73_O15350-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120045_p73_O15350-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.21 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913617

Product Specific Information

Positive test controls include: 293T. The target is usually found in the following locations: Cytoplasm, Nucleus.

Immunogen sequence: YHADPSLVSF LTGLGCPNCI EYFTSQGLQS IYHLQNLTIE DLGALKIPEQ YRMTIWRGLQ DLKQGHDYST AQQLLRSSNA ATISIGGSGE LQRQRVMEAV HFRVRHTITI PNRGGPGGGP DEWADFGFDL PDCKARKQPI KEEFTEAEIH

Target Information

P73 (TP73) participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.