Thermo Fisher Scientific p73 Polyclonal Antibody
Human 및 Mouse 반응성을 가진 Rabbit Polyclonal p73 항체로, WB, IHC, ICC/IF, ELISA에 사용 가능. 고순도 Affinity Chromatography 정제, 액상 형태로 PBS와 50% glycerol buffer에 보관. DNA 손상 반응 및 세포 사멸 연구에 적합.
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Thermo Fisher Scientific p73 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 487–636 of human TP73 (NP_005418.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.21 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913617 |
Product Specific Information
- Positive test controls: 293T
- Localization: Cytoplasm, Nucleus
Immunogen sequence:
YHADPSLVSF LTGLGCPNCI EYFTSQGLQS IYHLQNLTIE DLGALKIPEQ YRMTIWRGLQ DLKQGHDYST AQQLLRSSNA ATISIGGSGE LQRQRVMEAV HFRVRHTITI PNRGGPGGGP DEWADFGFDL PDCKARKQPI KEEFTEAEIH
Target Information
P73 (TP73) participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, while isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. It may act as a tumor suppressor protein.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-120045_p73_O15350-1_Rabbit.svg, PA5-120045_p73_O15350-1_Rabbit_PDP.jpeg)
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