Thermo Fisher Scientific Nrf2 Polyclonal Antibody
Nrf2 단백질을 검출하기 위한 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Affinity Chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 243–400 of human NRF2 (NP_0061552) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.13 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2913620 |
Product Specific Information
Immunogen sequence:
SPHFLNAFED SFSSILSTED PNQLTVNSLN SDATVNTDFG DEFYSAFIAE PSISNSMPSP ATLSHSLSEL LNGPIDVSDL SLCKAFNQNH PESTAEFNDS DSGISLNTSP SVASPEHSVE SSSYGDTLLG LSDSEVEELD SAPGSVKQNG PKTPVHSS
Positive test controls: HeLa, NIH/3T3
Localization: Cytoplasm, Nucleus, Cytosol
Target Information
Nfr1 (also designated TCF11), Nrf2, and Nfr3 are bZIP transcription factors that heterodimerize with Maf proteins to bind MARE (Maf recognition elements) sequences.
Nrf2 is widely expressed and translocates to the nucleus upon exposure to xenobiotics and antioxidants, which trigger its release from the repressor protein Keap1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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