Thermo Fisher Scientific APOE Polyclonal Antibody
APOE 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot, IHC, ICC, ELISA 등 다양한 응용 가능. 인체 및 설치류 반응성, 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 연구용 적합.
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- PA5120043
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Thermo Fisher Scientific APOE Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 41–307 of human APOE (NP_000032.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.59 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913615 |
Product Specific Information
- Positive test controls: HepG2, Mouse brain, Rat brain
- Localization: Secreted
Immunogen sequence:
GQRWELALGR FWDYLRWVQT LSEQVQEELL SSQVTQELRA LMDETMKELK AYKSELEEQL TPVAEETRAR LSKELQAAQA RLGADMEDVC GRLVQYRGEV QAMLGQSTEE LRVRLASHLR KLRKRLLRDA DDLQKRLAVY QAGAREGAER GLSAIRERLG PLVEQGRVRA ATVGSLAGQP LQERAQAWGE RLRARMEEMG SRTRDRLDEV KEQVAEVRAK LEEQAQQIRL QAEAFQARLK SWFEPLVEDM QRQWAGLVEK VQAAVGT
Target Information
Apolipoprotein E (Apo E) is crucial in lipid metabolism and is a component of various plasma lipoprotein-lipid particles. It is synthesized in the liver, brain, spleen, and kidney, with high concentrations in interstitial fluids. Apo E facilitates cholesterol transport between cells and contributes to the formation of very low-density lipoprotein (VLDL) and chylomicrons. The Apo E gene is located on chromosome 19 at position 19q13.2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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