Thermo Fisher Scientific NPY Monoclonal Antibody (3B5)
NPY 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며, PBS(pH 7.4) 용액에 보존됩니다. 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B5 |
| Immunogen | NPY (AAH29497, 29 a.a.–97 a.a.) partial recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
YPSKPDNPGE DAPAEDMARY YSALRHYINL ITRQRYGKRS SPETLISDLL MRESTENVPR TRLEDPAMW
Target Information
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function.
The neuropeptide functions through G protein-coupled receptors to:
- Inhibit adenylyl cyclase
- Activate mitogen-activated protein kinase
- Regulate intracellular calcium levels
- Activate potassium channels
A polymorphism in this gene (Leucine 7 → Proline) is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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