
Thermo Fisher Scientific CD26 Monoclonal Antibody (BA5b)
인간 CD26 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Flow Cytometry 등에 사용 가능. 비결합(Unconjugated) 형태이며, Protein A로 정제된 액상 시약. PBS buffer에 sodium azide 포함, 4°C 보관.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BA5b |
| Immunogen | A human T cell clone |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154490 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD26, a 110 kDa type II transmembrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells, and macrophages.
Target Information
CD26 (dipeptidyl peptidase IV, DPP IV; adenosine deaminase binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family.
It is expressed on lymphocytes and upregulated during T-cell activation, also found on activated B cells, NK cells, and epithelial tissues.
CD26 participates in:
- T-cell activation
- Cell adhesion with extracellular matrix (fibronectin, collagens)
- HIV infection mechanisms
It is identical to adenosine deaminase complexing protein-2 and functions as a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides.
Altered CD26 activity is linked to malignant transformation and tumor progression. Changes in CD26 density are also observed in monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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