Thermo Fisher Scientific CCDC22 Monoclonal Antibody (OTI5C1), TrueMAB
CCDC22 단백질을 인식하는 Mouse monoclonal 항체로, Western blot과 IHC(Paraffin)에서 검증됨. Human, Mouse, Rat에 반응. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C1 |
| Immunogen | Full length human recombinant protein of human CCDC22 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CCDC22 is a coiled-coil domain-containing protein that binds copines, calcium-dependent membrane-binding proteins involved in calcium signaling.
In rats, CCDC22 localizes in various brain regions (prefrontal and somatosensory cortex, dentate gyrus, thalamus) and spinal cord motor neurons after nerve injury, suggesting a role in neuronal injury response.
The human CCDC22 gene is a candidate gene for syndromic X-linked intellectual disability (XLID).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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