Thermo Fisher Scientific CCDC22 Monoclonal Antibody (OTI8B11), TrueMAB
CCDC22 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot에 적합합니다. Human, Mouse, Rat에 반응하며, 무보존제 동결건조 형태로 제공됩니다. 재구성 시 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B11 |
| Immunogen | Full length human recombinant protein of human CCDC22 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CCDC22 is a coiled-coil domain-containing protein that binds copines, which are calcium-dependent membrane-binding proteins involved in calcium signaling. In rat, CCDC22 localizes to several brain regions including the prefrontal and somatosensory cortex, dentate gyrus, and thalamus, as well as motor neurons of the spinal cord after sciatic nerve transection, suggesting a role in neuronal injury response.
The human CCDC22 gene has been identified as a novel candidate for syndromic X-linked intellectual disability (XLID).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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