Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI4H8), TrueMAB
TMEM173(STING) 단백질을 인식하는 Mouse Monoclonal Antibody(OTI4H8). Western Blot 및 IHC(Paraffin)에서 검증됨. Affinity chromatography로 정제된 액상 항체로, PBS/BSA/glycerol buffer에 보관. 선천면역 신호전달 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H8 |
| Immunogen | Full length human recombinant protein of human TMEM173 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
STING (TMEM173) is a 379-amino-acid signaling protein that plays a crucial role in innate immune signaling. It activates NF-κB and IRF3 transcription pathways to induce type I interferon (IFN-α and IFN-β) expression, establishing a strong antiviral state.
STING may function as a translocon influencing type I interferon induction and mediates apoptotic signaling via association with MHC-II. It is localized in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed across most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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