Thermo Fisher Scientific PLAUR Polyclonal Antibody, MaxPab
Thermo Fisher Scientific의 PLAUR Polyclonal Antibody는 인간 PLAUR(uPAR, CD87)에 특이적인 항체로 Western blot에 적합합니다. 액상 형태로 제공되며 PBS(pH 7.2)에 보존제가 없습니다. Affinity chromatography로 정제되어 고순도이며 -20°C에서 보관합니다.
- 카탈로그번호
- H00005329-B01P
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | PLAUR (NP_002650.1, 1–335 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MGHPPLLPLL LLLHTCVPAS WGLRCMQCKT NGDCRVEECA LGQDLCRTTI VRLWEEGEEL ELVEKSCTHS EKTNRTLSYR TGLKITSLTE VVCGLDLCNQ GNSGRAVTYS RSRYLECISC GSSDMSCERG RHQSLQCRSP EEQCLDVVTH WIQEGEEGRP KDDRHLRGCG YLPGCPGSNG FHNNDTFHFL KCCNTTKCNE GPILELENLP QNGRQCYSCK GNSTHGCSSE ETFLIDCRGP MNQCLVATGT HEPKNQSYMV RGCATASMCQ HAHLGDAFSM NHIDVSCCTK SGCNHPDLDV QYRSGAAPQP GPAHLSLTIT LLMTARLWGG TLLWT
Target Information
The urokinase-type plasminogen activator receptor (PLAUR/uPAR/CD87) regulates cell-surface plasminogen activation and plays an important role in normal and pathological processes.
Human PLAUR cDNA encodes 335 amino acids, including a signal peptide and a hydrophobic C-terminal portion, producing a highly glycosylated ~50 kD membrane-anchored protein.
PLAUR associates with SELL and β2 integrins in neutrophils, mediating calcium mobilization.
UPAR mRNA levels correlate with invasiveness and disease progression in endometrial carcinomas, serving as a prognostic marker for advanced stages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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